I just got this mouse today and it is an excellent mouse. The 3-way scroll works in Vista (I could not get it to work in XP). The wheel is programmable as well to varius keyboard functions such as F-keys, copy, paste, etc. Action is very smooth (adjustable speed) and the mouse buttons are low noise and very sensitive. The mouse is quite big and if you have a big hand like me, this is an ideal mouse. I recommend to try it, you can always return it. If you are lefthanded like me, the forward and back button (side buttons) are not repeated on the left, except for that it is suitable for left hand also. Oh yes, it's USB connector.