The Emmy Award-winning ladies of Wisteria Lane have even sharper fangs in the juicy fourth series of DESPERATE HOUSEWIVES, a primetime soap opera that takes aim at the dark side of suburban life. The fourth installment revolves around the return of Katherine Mayfair (Dana Delaney), a one-time neighborhood resident with an abusive past that she can never fully escape. Katherine joyfully reunites with her old friend, Susan (Teri Hatcher), who is unexpectedly expecting, but immediately clashes with Bree (Marcia Cross), who is pretending to be pregnant so that she can soon raise her teenage daughter's child as her own. Meanwhile, Lynette's (Felicity Huffman) cancer creates obstacles in both her marriage and her friendships, and Edie (Nicollette Sheridan) continues to fight with Gabrielle (Eva Longoria Parker) over Carlos (Ricardo Antonio Chavira). Each delightfully twisty, catty storyline comes to a powerful conclusion in the season's controversial time-jumping finale, 'Free'. The 17 episodes included in this set feature guest appearances from John Slattery (MAD MEN) and Nathan Fillion (FIREFLY).