@ The Howard Johnson Inn Heritage Park - 2* Hotel, Kissimmee, Florida - Less than 20mins drive from Disneyworld 30mins from Universal Studios - £148 2 people 7 nights (room only)
Days Inn Orlando Maingate to Universal - @ Universal - £155 2 persons 7 nights including Breakfast - Pool - Family Friendly
Another deal from Hotelopia, I've searched May dates and the above came up for a stay between 12th & 19th May 2009.
Check BA, Virgin Atlantic, Orbitz etc to compare flights, or use skyscanner to do it for you
Again, you can pay more for nicer hotels, (check out the Orlando / Florida Deals on Hotelopia) but if you're travelling on a shoestring or just need a base while you explore Florida then this could be ideal