Prague is a great value city and I'm tempted by this deal myself over the bank holiday weekend in May. Leaving on 28th May (Sunday) and returning on 31st May (Wednesday) from Liverpool airport, great if like me you get the bank holiday off work!
There are lots of hotel choices in Prague but I've picked the Hotel Kavalir which is close to metro stops, has good reviews overall on Tripadvisor with a Travellers Choice Bargian award and includes breakfast and for less than £35 a night you can't go wrong. I did check other reviews and it seems to get favourable verified reviews on other sites too.
Getting from the airport to Prague is cheap and easy using public transport or you can also sort out private transfers of you don't want to use public transport.
Flights with Ryanair for 2 people from Liverpool £87.96
3 nights in Hotel Kavalir £104.10 book on Ebookers using 14% off code which can be found in the voucher section of HUKD.