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Based on the novel by Patrick McGrath, David Cronenberg's psychological drama follows Dennis "Spider" Cleg (Ralph Fiennes), a mentally disturbed man who has just been released from an asylum. Upon taking up residence in a seedy London apartment building, the already introverted Spider begins to retreat further into his own thoughts, shutting out the caretaker, Mrs. Wilkinson (Lynn Redgrave), and other eccentric tenants such as the wistful Terrence (John Neville).
Within the confines of his mind, the anxious Spider revisits his childhood and literally watches his younger self (Bradley Hall) as he interacts with his doting mother (Miranda Richardson) and distant father (Gabriel Byrne). As his visions of the past continue, tragedy strikes and the dark history of Spider's life is slowly revealed.