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Peter Parker (Toby Magure) is an ordinary guy who lives with his beloved aunt and uncle and quietly pines for the girl next door, Mary Jane (Kirsten Dunst). But when a genetically-modified 'super-spider' bites him while on a school trip, Peter develops unusual skills - fantastic acrobatic strength, supernatural awareness and a talent for web-spinning. It's not until tragedy strikes at home that Peter decides to use his new powers to fight crime under a secret identity: Spider-Man! When the evil Green Goblin (Willem Dafoe) attacks the good people of New York and endangers the life of Mary Jane, Peter commits himself to the ultimate tests: to thwart his arch-enemy and to win the heart of the girl that he loves.
Two years have passed, and the mild-mannered Peter Parker (Tobey Maguire) faces new challenges as he struggles to balance his life as the elusive superhero Spider-Man. Tormented by his secrets, Peter is in danger of losing all those that he holds dear. His love for MJ (Kirsten Dunst) becomes stronger and his friendship with Harry Osborn (James Franco) is complicated by the young Osborn's bitterness over his father's death. These relationships are now in danger of unraveling when he confronts a new nemesis, the brilliant Otto Octavius, (Alfred Molina) who has been reincarnated as the multi-tentacled "Doc Ock."
Spider-Man 3 reunites the cast and filmmakers from the first two blockbuster adventures for a web of secrets, vengeance, love, and forgiveness that will transport worldwide audiences to thrilling new heights on May 4 2007. In Spider-Man 3, based on the legendary Marvel Comics series, Peter Parker has finally managed to strike a balance between his devotion to M.J. and his duties as a superhero. But there is a storm brewing on the horizon. When his suit suddenly changes, turning jet-black and enhancing his powers, it transforms Peter as well, bringing out the dark, vengeful side of his personality that he is struggling to control. Under the influence of the suit, Peter becomes overconfident and starts to neglect the people who care about him most. Forced to choose between the seductive power of the new suit and the compassionate hero he used to be, Peter must overcome his personal demons as two of the most-feared villains yet, Sandman and Venom, gather unparalleled power and thirst for retribution to threaten Peter and everyone he loves.