The Thriller hitmaker is making a return to the stage in July with a 50-date run at the O2 Arena for his This Is It comeback tour.
And Jackson is eager for the Bleeding Love singer to step in and sing his sister Janet's vocals on his 1995 hit Scream, according to The Sun newspaper.
A source tells the publication, Michael has a list of singers he feels could do Janet justice - and Leona is top.
He hasnt approached her yet but hes a big fan of everything she has achieved. Shes massive all around the world and he feels this duet would give both their careers an even bigger boost.