NEXIUM Control 20mg Tablets, (14 Tablets) £5.59 Prime / £9.58 Non Prime @ Amazon
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NEXIUM Control 20mg Tablets, (14 Tablets) £5.59 Prime / £9.58 Non Prime @ Amazon

27
Found 30th Mar 2017
Even cheaper than before. Paid £6.99 weeks ago, same price as the 7 tablets. Cheapest I can find it for is around £8. Average is £10. Hope it helps someone
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heat, however...

1. go and see your doctor,
2. these can affect other drugs, e.g. letting anti diahorrea (opiates) drugs to cross the gut into your blood.
99rb

heat, however...1. go and see your doctor, 2. these can affect other … heat, however...1. go and see your doctor, 2. these can affect other drugs, e.g. letting anti diahorrea (opiates) drugs to cross the gut into your blood.


Loperamide is an opioid antagonist, not an opiate, and as you say does not cross blood brain barrier.
Had not heard of an interaction with omeprazole. Got a link to where you read this?
I take oneperazole
99rb

heat, however...1. go and see your doctor, 2. these can affect other … heat, however...1. go and see your doctor, 2. these can affect other drugs, e.g. letting anti diahorrea (opiates) drugs to cross the gut into your blood.


Can you expand on this please
I would not recommend this medication to anyone who can manage on standard antacids. Once your body gets used to them on a daily basis they're a nightmare to come off. Ideal for those who find they get no relief from those though...and a decent price. (This is my experience only and I take PPIs twice a day).
i need this.
I used to buy this until my GP prescribed the same thing on repeat, the generic esomeorazole 56 tablets a month for £10 via the NHS PPC scheme.
callum84

Loperamide is an opioid antagonist, not an opiate, and as you say does … Loperamide is an opioid antagonist, not an opiate, and as you say does not cross blood brain barrier.Had not heard of an interaction with omeprazole. Got a link to where you read this?



​I'm tea total, took the two together and felt noticeably trippy/tipsy. After googling found anecdotal suggestions that this was the cause. I haven't found any formal interaction documentation but as loperamide isn't a long term drug I was guessing tests may not have been done. I imagine pharma will test the obvious drugs but will not test all combinations as that would be prohibitive.
99rb

​I'm tea total, took the two together and felt noticeably trippy/tipsy. A … ​I'm tea total, took the two together and felt noticeably trippy/tipsy. After googling found anecdotal suggestions that this was the cause. I haven't found any formal interaction documentation but as loperamide isn't a long term drug I was guessing tests may not have been done. I imagine pharma will test the obvious drugs but will not test all combinations as that would be prohibitive.


Loperamide is a long term drug for some people - as is a loperamide/omeprazole/codeine combination - which I have been taking for 4 years
callum84

Loperamide is an opioid antagonist, not an opiate, and as you say does … Loperamide is an opioid antagonist, not an opiate, and as you say does not cross blood brain barrier.Had not heard of an interaction with omeprazole. Got a link to where you read this?



​further reading, omeperazole also inhibits P-glycoprotein, this is associated with BBB blocking loperamide. I'm no expert, doctor or junkie so I might have just felt lightheaded after the squits.... oO
amin-credible

I used to buy this until my GP prescribed the same thing on repeat, the … I used to buy this until my GP prescribed the same thing on repeat, the generic esomeorazole 56 tablets a month for £10 via the NHS PPC scheme.


Can this be sold over the counter ?
99rb

​I'm tea total, took the two together and felt noticeably trippy/tipsy. A … ​I'm tea total, took the two together and felt noticeably trippy/tipsy. After googling found anecdotal suggestions that this was the cause. I haven't found any formal interaction documentation but as loperamide isn't a long term drug I was guessing tests may not have been done. I imagine pharma will test the obvious drugs but will not test all combinations as that would be prohibitive.


Not doubting you, was simply curious.
ukmonkey

Can this be sold over the counter ?


No, Nexium have the rights to it for a period of time I believe may be a good while before we see supermarkets doing own brand versions like we get with analgesics and NSAIDs
used to take these then switched to decaff coffee and havent needed them since. I am not a big coffee drinker but cutting out caffine cured me of acid reflux.
heat for price good old amazon
amin-credible

No, Nexium have the rights to it for a period of time I believe may be a … No, Nexium have the rights to it for a period of time I believe may be a good while before we see supermarkets doing own brand versions like we get with analgesics and NSAIDs


Esomeprazole (Nexium) is patented, but omeprazole is a generic drug. If your doctor attempts to prescribe you esomeprazole, you should insist on omeprazole.* They are ridiculously close to being the same drug (there were claims of evergreening on the manufacturer's part), but the former currently costs the NHS almost three times the latter.

I've seen esomeprazole for sale in supermarkets, and omeprazole for sale on pharmacy shelves. Pick whichever is cheaper; currently you still pay multiples of what the NHS pays irrespective of patents.

* I'm not a doctor, etc.
Edited by: "atomicphreak" 3rd Apr 2017
Top tip for heartburn when going to bed, sleep on your left handside....thank me later
long term it's thought can increase fracture risk, increase susceptibility to c diff bug, hypomagnesemia.
Agree with the above "see a doctor".
If normal stuff e.g. Gaviscon not controlling it, and long standing/ongoing heartburn symptoms just see your GP*

*I actually AM a doctor & OTC PPIs make me uncomfortable as people with serious problems then buy it for years and don't come and tell us!
ILIKEBARGAINSME

Can you expand on this please



Do, what he says. Just go see a doctor. They are there to help you and one should not feel embarassed about any issues we may have.
I've been on a PPI for about 10 years now, currently Pantoprazole 20mg a day 56 tablets on repeat, go see your quack if you need a PPI.
amin-credible

No, Nexium have the rights to it for a period of time I believe may be a … No, Nexium have the rights to it for a period of time I believe may be a good while before we see supermarkets doing own brand versions like we get with analgesics and NSAIDs



​nexium will go generic soon, patent has (or is just about to) expire
As said above take these for a while and you will be stuck on them, try coming off them and acid rebound will be worse than it was before, better off with Zantac
stave84

Agree with the above "see a doctor".If normal stuff e.g. Gaviscon not … Agree with the above "see a doctor".If normal stuff e.g. Gaviscon not controlling it, and long standing/ongoing heartburn symptoms just see your GP**I actually AM a doctor & OTC PPIs make me uncomfortable as people with serious problems then buy it for years and don't come and tell us!


It's because they can't get an appointment
moob

It's because they can't get an appointment



Haha. Well that's a fair argument for a week or 2 but not 6-12months. As it happens I don't work in a traditional GP setup. People I see called for an appointment never more than 6hrs earlier. Often within an hour. Sadly huge numbers of appointments in GP wasted by people with a cold who want a "cure". Or who don't show up (although I like those, it's called catch up time!)
stave84

Agree with the above "see a doctor".If normal stuff e.g. Gaviscon not … Agree with the above "see a doctor".If normal stuff e.g. Gaviscon not controlling it, and long standing/ongoing heartburn symptoms just see your GP**I actually AM a doctor & OTC PPIs make me uncomfortable as people with serious problems then buy it for years and don't come and tell us!



​It's funny you say that. I had heartburn for about 3 years then went to see a doctor. He did one test (something about infection of the stomach - nothing serious apparently) then the test came back negative. The doctor said it's unlikely to be anything serious (due to my age, 24) and refused to do any more tests and refused to prescribe me antacids. So here I am 18 months down the still struggling with heart burn. Not had great experiences with doctors...
Esomeprazole is generic now (ie cheap but just as good). Theoretically decreases effectiveness of platelet blocker clopidogrel. As others have said, ranitidine is cheaper and 98% as good. You won't get withdrawal (rebound) acid unless you've been on them for a long time. Goose112 - you've tested negative for h. pylori bacteria that cause ulcers but it doesn't mean you don't have acid reflux. Pressure on GPs to not prescribe antacids. Start with Gaviscon over the counter.
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