Two socially inept teenage boys are about to graduate high school. Evan (Michael Cera) is sweet, smart, and generally terrified. Seth (Jonah Hill) is foul mouthed, volatile, and all-consumed with the topic of human sexuality. Seth and Evan want nothing more than to lose their virginity before they head off to college. To do that, though, they need to get liquor for the big party that night. With the help of their friend Fogell, a.k.a. McLovin (Christopher Mintz-Plasse), and his fake I.D., the three of them go on a hilarious chase for that elusive booze, dodging incompetent cops (Knocked Up's Seth Rogen and Saturday Night Live's Bill Hader), angry neighbors and jealous boyfriends!