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    The Drug Trial: Emergency at the Hospital (BBC 2 9pm)

    Banned
    On Monday, March 13, 2006, eight healthy young men took part in a clinical trial of an experimental drug known as TGN1412. The drug was intended to treat leukaemia and had already been successfully tested on monkeys but never on humans. However, it went terribly wrong, leaving six of the volunteers fighting for their lives. This drama-documentary tells the story of one of the most infamous medical emergencies in recent British history.

    Should be interesting this. What's the overall thoughts on people doing this for some quick cash, more interstingly, has anyone here ever taken part in one?

    Seems a very silly thing to do!

    54 Comments

    I remember this happening, there was always adverts wanting Guinea pigs for these trials, after this I think it put people off a bit.

    Ive got a mother in law willing to do this trail please send me the drugs in plain packaging.

    I think experimental drugs should be trialled on prisoners. As long as there is no way for them to end up with super powers.

    Original Poster Banned

    shadey12

    I remember this happening, there was always adverts wanting Guinea pigs … I remember this happening, there was always adverts wanting Guinea pigs for these trials, after this I think it put people off a bit.



    You can just imagine some of the tests that those poor animals are subjected to. The 2 guys who got the plaebo must appreciate life a bit more now at least.


    Edited by: "MrScotchBonnet" 21st Feb

    Original Poster Banned

    jax619

    Ive got a mother in law willing to do this trail please send me the drugs … Ive got a mother in law willing to do this trail please send me the drugs in plain packaging.


    Lol, you won't find TGN1412 anywhere now but I know fo a few others. oO X)

    Original Poster Banned

    jax619

    I think experimental drugs should be trialled on prisoners. As long as … I think experimental drugs should be trialled on prisoners. As long as there is no way for them to end up with super powers.



    I wouldn't even feel comfortable with that to be honest, I understand they need to be tested, it's a shame there is no other option.

    MrScotchBonnet

    Lol, you won't find TGN1412 anywhere now but I know fo a few others. oOX)



    I've just asked her and she wants to try them all. She's more interested in trying to ones you can mix with a cup of tea and it not change the taste.

    Banned

    jax619

    I think experimental drugs should be trialled on prisoners.




    Is it cool & trendy now to become more & more like members of the Nazi Party?

    shadey12

    I remember this happening, there was always adverts wanting Guinea pigs … I remember this happening, there was always adverts wanting Guinea pigs for these trials, after this I think it put people off a bit.



    Actually it increased the amount of people applying to be part of drug trials as it publicised the £5,000 the men were being paid.

    YouDontWantToKnow

    Is it cool & trendy now to become more & more like members of the Nazi … Is it cool & trendy now to become more & more like members of the Nazi Party?



    I don't know, is it cool and trendy now to become more and more like members of the Nazi party?

    Original Poster Banned

    rose_cat_jr

    Actually it increased the amount of people applying to be part of drug … Actually it increased the amount of people applying to be part of drug trials as it publicised the £5,000 the men were being paid.



    That seems unlikely, no one can value 5k more than their life.

    MrScotchBonnet

    That seems unlikely, no one can value 5k more than their life.




    Have you ever spent a day in Blackpool?

    Banned

    MrScotchBonnet

    That seems unlikely, no one can value 5k more than their life.



    Pretty sure those effected got quite a lot of compo too

    Original Poster Banned

    YouDontWantToKnow

    Pretty sure those effected got quite a lot of compo too



    Really? I thought the whole point in the cash incentive was to waive your rights to anything like that?

    Banned

    MrScotchBonnet

    Really? I thought the whole point in the cash incentive was to waive your … Really? I thought the whole point in the cash incentive was to waive your rights to anything like that?



    Everyone has a duty of care regardless of what is written in a contract. Yep. They got compo.

    Original Poster Banned

    YouDontWantToKnow

    Everyone has a duty of care regardless of what is written in a contract. … Everyone has a duty of care regardless of what is written in a contract. Yep. They got compo.



    Ordered through the court?

    hotradiotimesuk

    Original Poster Banned

    craigstephens

    hotradiotimesuk



    I just thought it was an interesting subject, sorry.

    MrScotchBonnet

    That seems unlikely, no one can value 5k more than their life.



    Are these not people who are unfortunately dying anyway?
    Surely it would be illegal to give this to someone who was not dying, even if they gave consent.

    If I were dying I'd take a chance at life and 5k, and in the worst case scenario, it would cover my funeral costs.

    fps_d0minat0r

    Are these not people who are unfortunately dying anyway?Surely it would … Are these not people who are unfortunately dying anyway?Surely it would be illegal to give this to someone who was not dying, even if they gave consent.If I were dying I'd take a chance at life and 5k, and in the worst case scenario, it would cover my funeral costs.



    ​they were healthy.

    Banned

    MrScotchBonnet

    Ordered through the court?



    I dont know. I am sure it will say in the program

    MrScotchBonnet

    You can just imagine some of the tests that those poor animals are … You can just imagine some of the tests that those poor animals are subjected to. The 2 guys who got the plaebo must appreciate life a bit more now at least.



    ​they'd already tested it on animals, they were fine and went to live on a farm in the country and died of old age.

    Original Poster Banned

    YouDontWantToKnow

    I dont know. I am sure it will say in the program



    Well you better find out just incase it doesn't.

    I'm not watching it until 10.

    Original Poster Banned

    shadey12

    ​they'd already tested it on animals, they were fine and went to live on a … ​they'd already tested it on animals, they were fine and went to live on a farm in the country and died of old age.



    Well that just proves ''tested on animals'' means absolutely nothing.

    YouDontWantToKnow

    I dont know. I am sure it will say in the program



    ​i think one lost all his fingers and toes. he got a few million I think, if it was the same case.

    Original Poster Banned

    shadey12

    ​i think one lost all his fingers and toes. he got a few million I think, … ​i think one lost all his fingers and toes. he got a few million I think, if it was the same case.




    Wow, that much.

    MrScotchBonnet

    Well that just proves ''tested on animals'' means absolutely nothing.



    ​its because animals are sterile and never exposed to germs, if a test subject was 20years old, they've been exposed to other drugs and outside influences which can react to the drugs in the trial.

    Banned

    shadey12

    ​i think one lost all his fingers and toes. he got a few million I think, … ​i think one lost all his fingers and toes. he got a few million I think, if it was the same case.



    I know one got a couple of million.

    I remember it at the time & what the drug did is destroy white blood cells leaving them with pretty much zero immunity

    YouDontWantToKnow

    I know one got a couple of million. I remember it at the time & what the … I know one got a couple of million. I remember it at the time & what the drug did is destroy white blood cells leaving them with pretty much zero immunity



    ​they have no idea what the future holds either.
    not something I'd fancy kicking round inside me.

    This happened at my local hospital Northwick Park Hospital in Harrow.
    Can still remember the publicity when it happened.

    Why should any of them get compensation, they signed up for it and got paid, you take your chances surely, if you put money on the lottery or horses and loose, you dont get your money back if it goes wrong.

    Edited by: "Daytrader" 21st Feb

    Daytrader

    Why should any of them get compensation, they signed up for it and got … Why should any of them get compensation, they signed up for it and got paid, you take your chances surely, if you put money on the lottery or horses and loose, you dont get your money back if it goes wrong.



    ​i think organ failure, limb loss and future complications in life didn't come into the contract.

    shadey12

    ​i think organ failure, limb loss and future complications in life didn't … ​i think organ failure, limb loss and future complications in life didn't come into the contract.


    Im sure the contract did say that there was a risk.

    Banned

    Daytrader

    Im sure the contract did say that there was a risk.



    A risk not a 100% surety.

    And they injected all of them within minutes rather than one every day & that in itself is negligence .

    Edited by: "YouDontWantToKnow" 21st Feb

    YouDontWantToKnow

    A risk not a 100% surety. And they injected all of them within minutes … A risk not a 100% surety. And they injected all of them within minutes rather than one every day & that in itself is negligence .



    Basically what you said there - the hospital trial was negligent as they injected all within minutes.


    fps_d0minat0r

    Are these not people who are unfortunately dying anyway?Surely it would … Are these not people who are unfortunately dying anyway?Surely it would be illegal to give this to someone who was not dying, even if they gave consent.If I were dying I'd take a chance at life and 5k, and in the worst case scenario, it would cover my funeral costs.



    All drug trials are done via animals, and then healthy subjects at incredibly low doses, and then healthy subjects on "therapeutic" doses (All looking at the safety profile of the drug, what side effects it produces) and then on people with illness (Is the drug actually effective?)

    If animal dies because of the drug --> Drug does not proceed to humans
    Theoretically, a tiny dose of a drug shouldn't do too much harm, hence give an absolutely minuscule amount to see whether there are side effects. The problem is, these chemicals have never been tried in humans so there is the small possibility that the chemical could be very, very toxic.

    Edited by: "Firefly1" 21st Feb

    YouDontWantToKnow

    And they injected all of them within minutes rather than one every day & … And they injected all of them within minutes rather than one every day & that in itself is negligence .


    I remember this happening and that was exactly my thoughts at the time, it was incredibly irresponsible to give an experimental drug to all the volunteers at the same time, because then they all became ill at the same time and overwhelmed the resources at the hospital for dealing with it.
    If they'd have spaced it out and given the drug to each volunteer at intervals, they could have stopped the trial when the first volunteer became ill and had more time to deal with the situation.

    Edited by: "Delbert.Grady" 21st Feb

    Banned

    Delbert.Grady

    I remember this happening and that was exactly my thoughts at the time, … I remember this happening and that was exactly my thoughts at the time, it was incredibly irresponsible to give an experimental drug to all the volunteers at the same time, because then they all became ill at the same time and overwhelmed the resources at the hospital for dealing with it.If they'd have spaced it out and given the drug to each volunteer at intervals, they could have stopped the trail when the first volunteer became ill and had more time to deal with the situation.



    Too true.

    If they spaced out the injections only one of them would have been injected & become ill.

    YouDontWantToKnow

    A risk not a 100% surety. And they injected all of them within minutes … A risk not a 100% surety. And they injected all of them within minutes rather than one every day & that in itself is negligence .


    Yeh you make a good point there, watching it more on tv has made me rethink a little, i guess they should not have done it for the money in the first place, but greed gets us all sometimes, these trials should not offer money in the first place, should always be people that want to help the medical world regardless of monetary gain, but there was definitely negligence involved.

    Edited by: "Daytrader" 21st Feb

    Will this be added to my thread

    Original Poster Banned

    YouDontWantToKnow

    I dont know. I am sure it will say in the program



    Nope.
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